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July 6, 2025, 5:46 a.m. -  taologaetsewe
In most cases of HAE, this is due to mutations in the gene that provides directions for making a protein known as C1 inhibitor, which usually stops the activity of an enzyme referred to as kallikrein. When C1 inhibitor protein is faulty or lacking, kallikrein becomes overactive and triggers the excessive manufacturing and release of one other signaling molecule known as bradykinin. Too much bradykinin, in turn, causes blood vessels to become more permeable and leak fluid into close by tissues, leading to swelling. This is because Anavar drains out water accumulation in between the muscle and skin

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